Surface Properties and Biocompatibility of Anodized Titanium with a Potential Pretreatment for Biomedical Applications

The effects of anodized titanium (Ti) with a potential hydrogen fluoride (HF) acid pretreatment through cathodization on the formation nano-porous Ti dioxide (TiO2) layer were characterized using field-emission scanning electron microscopy, grazing incidence X-ray diffractometer, and contact angle goniometer. biocompatibility was determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) test. Analytical results found that well-aligned structure formed surface HF concentration above 0.5%. Microstructure generated anodization composed anatase rutile phases, while sample 0.5% presented excellent hydrophilicity surface. An in-vitro also indicated osteoblast cells grown increased increase culture time. filopodia not only adhered flat, but tightly grabbed for promoting cell adhesion proliferation. Therefore, can form functionalized great biomedical applications, particularly dental implants.